Piotr Walecki, PhD
Research Areas
- Immersive and Spatial Technologies in Medicine (VR/AR/MR)
Research on the application of virtual, augmented, and mixed reality, holography, spatial visualization, and 3D technologies in medicine. This work includes the use of immersive technologies in medical education, anatomy teaching, simulation of clinical and surgical procedures, and planning and support of medical interventions, as well as the assessment of acceptance, usability, cognitive workload, and tolerability of XR technologies. Selected publication titles: (Virtual Reality from a Biocybernetic Perspective; Applications of Generative Technologies in Medicine: Holographic Imaging and Augmented Reality in Telemedicine; Holography as a Progressive Revolution in Medicine; Overview of the Holographic-Guided Cardiovascular Interventions and Training: A Perspective; Application of Holography and Augmented Reality Based Technology to Visualize the Internal Structure of the Dental Root: A Proof of Concept; Assessment of the Utility of Mixed Reality in Medical Education; From Traditional to Immersive: The Impact of 3D Technologies on Medical Student Learning; Transforming Anatomy Education with Mixed Reality: A Curriculum-Based Study Using a Holographic Anatomy Software Suite.) - Neurobiology and Neuropsychology of Addiction
Research on the mechanisms of substance-related and behavioral addictions, with particular emphasis on reward-system function, executive control, impulsivity, risk assessment, and decision-making. Investigation of the neuropsychological and psychophysiological effects of opioid substitution treatment and the biological determinants of addiction-related behavior. Selected publication titles: (Risk Behavior in Opioid-Dependent Individuals after the Administration of a Therapeutic Dose of Methadone; Evaluation of Risk Behavior in Gambling Addicted and Opioid Addicted Individuals; Improvement of Saccadic Functions after Dosing with Methadone in Opioid Addicted Individuals; Opioid Dependence and Substitution Treatment from a Neurobiological Perspective; Adipokines as Potential Markers of Addiction; Speech and Music Stimuli in Studies of Individuals with Addiction; Prospects for the Use of Music and Speech in the Diagnosis and Treatment of Addiction; Effects of BF-HRV of Opioid-Dependent Persons with Pathological Gambling; Disturbances of Eyeball Movements in HIV Positive and HIV Negative Opioid Addicted Individuals before and after the Administration of Therapeutic Dose of Methadone.) - Saccadometry and Quantitative Analysis of Oculomotor Function
Research on eye movements, particularly saccadic and antisaccadic parameters, and their use as quantitative biomarkers of central nervous system function. Application of oculomotor methods in neurology, psychiatry, and neuropsychology, including studies of neurodegenerative diseases, psychiatric disorders, and addiction. Selected publication titles: (Direction-dependent Saccadic Waveform Asymmetry; The Influence of Coffee on Eyeball Movement; Dynamics of Eye Movements in Deaf and Hard-of-Hearing Individuals; Oculomotor Function in the Identification of Mental Function Disorders; Saccadic Refixation in the Diagnosis of Hyperkinetic Disorder in Adults; Improvement of Saccadic Functions after Dosing with Methadone in Opioid Addicted Individuals; Oculomotor Disturbances in HIV-Positive Individuals Treated with Methadone; Decrease of Velocity and Acceleration of Fast Eye Movement after the Administration of Methadone; Disturbances of Eyeball Movements in HIV Positive and HIV Negative Opioid Addicted Individuals before and after the Administration of Therapeutic Dose of Methadone; Grade Correspondence Cluster Analysis Applied to Classify Saccadic Eye Movements in Alzheimer’s Disease, Parkinson Disease and Schizophrenia.) - Artificial Intelligence, Medical Informatics, and Telemedicine
Research on the application of artificial intelligence and information technologies in medicine, including computer-assisted diagnosis and clinical decision support, medical knowledge representation and processing, expert systems, medical databases, and telemedicine. This area also encompasses the use of emerging computational technologies for modeling, analyzing, and interpreting biomedical data. Selected publication titles: (Theoretical and Practical Problems of Artificial Intelligence; Biologization of Computer Science; Biologization within the Technical and Computer Sciences; TDCHD: An Advanced Medical Teledatabase Solution; Telemedical Database of Hodgkin Disease; Telemedical Databases: Theory and Practice; Neuroinformatics Databases; Abductive Logic Programming in Medical Diagnosis; Applications of Generative Technologies in Medicine: Holographic Imaging and Augmented Reality in Telemedicine.) - Logic, Abduction, and Formal Models of Reasoning
Research on the formal structures of reasoning, particularly abductive inference, non-monotonic logics, and methods for representing incomplete and uncertain knowledge. Application of formal reasoning models to medical diagnosis, medical semiotics, decision-support systems, knowledge representation, and artificial intelligence. Selected publication titles: (Application of Abductive Reasoning in the Design of Medical Semiotics Models; Abductive Reasoning in Computer-Assisted Medical Diagnosis; Abductive Reasoning and Medical Diagnosis; Abductive Logic Programming in Medical Diagnosis; Nonmonotonic Logics as a Formalized Model of Human Thinking: Associative and Interpretative Representational Theory of Mind; Phenomenology of Semantics and the Problem of the Existence of Universals.) - Philosophy and Methodology of Science
Research on the epistemological and methodological foundations of the natural and technical sciences, with particular emphasis on the relationship between reality and its scientific representation. This work addresses determinism, causality, predictability, computability, scientific modeling, reduction and explanation, as well as the status of the observer, subjectivity, self-reference, and the limits of scientific knowledge. Selected publication titles: (Representing Reality by Means of Different Types of Variables; Humanistic Aspects of the Philosophy of Being and Anthropic Cosmology; The Localized and Globalist Soul; Phenomenology of Semantics and the Problem of the Existence of Universals; Nonmonotonic Logics as a Formalized Model of Human Thinking: Associative and Interpretative Representational Theory of Mind.) - Neuroinformatics and Mathematical Modeling of the Nervous System
Application of mathematical, computational, and information-science methods to the analysis of the organization and functioning of the nervous system. Research includes modeling of neuronal structures and neurophysiological processes, neuroimaging data analysis, fractal geometry, cellular automata, and quantitative methods for describing complex biological structures. Selected publication titles: (Fractal Measures in Neuroimaging; Lacunarity: Fractal Measures in Neuroimaging; Application of Fractal Geometry in Neuroanatomy; A Fractal Method for Describing Neuronal Shape and Growth Based on Probabilistic Algorithms with Attraction Regions; Cellular Automaton Analysis of the Spatial Distribution of Cell Bodies in the Cerebral Cortex; Neuroinformatics Databases; Direction-dependent Saccadic Waveform Asymmetry; Grade Correspondence Cluster Analysis Applied to Classify Saccadic Eye Movements in Alzheimer’s Disease, Parkinson Disease and Schizophrenia.) - Perception, Consciousness, and Cognitive Processes
Research on the neurobiological, psychophysiological, and informational foundations of perception and cognition. This area encompasses speech and music perception, sensory information processing, consciousness, subjectivity, and the relationships among neural processes, cognitive representation, and conscious experience. Selected publication titles: (Speech Perception: Toward Understanding of Consciousness; Speech Perception: Analysis of Evoked Potentials in Auditory Processing Disorders; Speech and Music Stimuli in Studies of Individuals with Addiction; The Speech-to-Song Illusion as a Tool for Creating Stimuli for Comparative Studies of Speech and Music; The Predictive Role of Cortico-Subcortical Loops in the Processing of Tonal Music Structure; Prospects for the Use of Music and Speech in the Diagnosis and Treatment of Addiction; Phenomenology of Semantics and the Problem of the Existence of Universals; The Localized and Globalist Soul.) - Nutrition, Metabolism, and Brain–Body Interactions
Research on the relationships among nutritional status, metabolism, nervous-system function, cognition, and disease. This area includes the gut–brain axis, microbiome-related mechanisms, metabolic and nutritional determinants of cognitive and behavioral function, and nutritional disturbances and malnutrition risk in selected clinical populations, including oncology. Selected publication titles: (Adipokines as Potential Markers of Addiction; publications on nutritional behavior in individuals with addiction, the gut–brain axis and microbiome, nutrition in neurodevelopmental disorders, and nutritional risk assessment in patients with cancer.)
